Looks the recent Trump Health-Care flop has produced big ripples in Wallstreet as reports are indicating that Wall Street futures have underlined a global market sell-off on Monday as investors being concerned over the potential knock-on effects of U.S. President Donald Trump‘s surprise failure to deliver on health-care reform.

So how bad is it? Sources indicate that Dow futures were set for triple-digit losses, down around 150 points at 8:45 a.m. ET, after Republicans dramatically pulled their health-care bill on Friday. “The market’s patience is wearing thin,” Vasileios Gkionakis, head of global FX strategy at Unicredit, told CNBC on Monday. “It definitely doubts the U.S. administration’s ability to push forward (with) this so much talked and discussed agenda including the fiscal stimulus, tax deregulation, tax cuts,” Gkionakis added.