Controlling the minds of others from a distance has long been a favourite science fiction theme – but recent advances in genetics and neuroscience suggest that we might soon have that power for real. Just over a decade ago, the bioengineer Karl Deisseroth and his colleagues at Stanford University published their paper on the optical control of the brain – now known as optogenetics – in which the firing pattern of neurons is controlled by light.
To create the system, they retrofitted neurons in mouse brains with genes for a biomolecule called channelrhodopsin, found in algae. Channelrhodopsin uses energy from light to open pathways so that charged ions can flow into cells. The charged ions can alter the electrical activity of neurons, influencing the animal’s behaviour along the way. READ MORE