(CNN) – A sixth person in the United States has died from lung disease related to vaping, Kansas health officials said Tuesday. The woman was older than 50 and had a history of health problems. She became seriously ill shortly after she started using e-cigarettes and her symptoms progressed rapidly. It’s not clear what type of vaping products she used, the Kansas Department of Health and Environment said. The death marks the first in the state, but raises even more concern about the safety and regulation of e-cigarettes.

The US Centers for Disease Control and Prevention, the Food and Drug Administration and state health departments have been investigating this outbreak. Health officials say they haven’t found a definitive cause or a clear connection between cases, but some are zeroing in on potential clues.
Here is what you need to know about vaping and vaping-related illnesses in the United States. As of Friday, there have been more than 450 possible cases of lung illness associated with using e-cigarettes reported to the CDC across 33 states and the US Virgin Islands. The numbers have been changing frequently. READ MORE