Once a bucket of genes linked to aging is removed, the lifespan of cells increases significantly, American scientists discovered during ten years of meticulous research, stressing that the results could be applied to humans. An “exhaustive, ten-year effort” allowed scientists at the Buck Institute for Research on Aging and the University of Washington to identify some 238 genes which could be targeted to improve human health and possibly extend life spans by 60 percent.
The paper was published on Thursday in the journal Cell Metabolism. The study was carried out on nearly 4,700 yeast strains, but a series of experiments involving roundworms allowed scientists to say that its results could be applied to humans, as well. “This study looks at aging in the context of the whole genome and gives us a more complete picture of what aging is,” said lead author Brian Kennedy, Buck Institute’s president and CEO, in the press release. “It also sets up a framework to define the entire network that influences aging in this organism.” CONTINUE